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Rectal Cancer Worsened by Oral Microbes, Research Indicates.

Could poor oral hygiene increase your risk for colorectal cancer? A new study suggests poor oral hygiene is connected to the health and well-being of yet another portion of the body. Colorectal cancer is the third most common cancer diagnosed in the United States, and the second most deadly, especially if regular screening for precancerous polyps is not regularly conducted.

Studies by the Garret Lab at Harvard have shown fusobacteria when present in the colon in high concentrations increase the risk of an individual for colon cancer. Fusobacteria are primarily oral pathogens which have been found to cause periodontal disease and ulcers. Furthermore, cancerous tissue in the colon has been found to be enriched with fusobacterium compared to surrounding, healthy tissue. This suggests that the bacteria are localizing somehow to the cancerous region in the colon from the mouth. But how?

One study from researchers at Hebrew University School of Dental Medicine attempted to discern this. Since it is well-established that oral bacteria can reach the bloodstream through bleeding gingiva or root tips, the researchers decided to inject a fusobacterial culture into the bloodstream and chemically track their movement. The bacteria were injected through a tail vein into two types of mouse; one group with precancerous colon growths, and the other with malignant colon cancer. After a brief waiting period, the colons of both groups were dissected and analyzed using fluoroscopy. The researchers found that the fusobacteria adhered in large quantities to both groups of tumors, and were not present in any heightened quantity in the control group. Furthermore, for the precancerous and cancerous group, the livers of both were found to have high concentrations of fusobacteria compared to the control. Colon cancer frequently metastasizes to the liver, and it is interesting that this seems to be pre-empted by the bacteria, suggesting a possible bacterial precursor or correlation to the metastatic process. This could prove highly useful in trying to predict or prevent the progression of colon cancer.

So what draws the bacteria to the tumor? Well, from studying a combination of human samples and mouse-model experiments, it appears a protein on the surface coat of the fusobacteria have a protein called Fap2 that binds to the sugar Gal-Gal-Nac, found in high concentrations on colorectal tumor cells. The protein Fap2 appears to mediate the colonization of tumor cells by the bacteria, and may represent a potential target for therapy. In any event, maintaining good oral hygiene and promptly seeing a dentist to address any infections in the mouth is reinforced by these findings.

Sources:
Nichols, H. (2016, August 10). “Colorectal tumors exacerbated by mouth microbes.” Medical News Today. Retrieved from http://www.medicalnewstoday.com/articles/312250.php.

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How early should your child have their first dental visit?

Bringing a child into this world isn’t easy and along with it comes some very important steps parents must take to ensure their child’s health. One step that may often go overlooked in this process is a visit during the child’s first year. It is essential to make that first dental appointment for your child will only help the process of protecting his or her teeth for years to come.

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Dental Implants: Some Information You Should Know

For some reason, or another you may have or may eventually be faced with the fact that you will lose a tooth. If this happens, it isn’t the end of the world. You have a few options when placed in this situation, but the latest and best solution is dental implants.

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Is Chewing Gum Good Or Bad For Teeth?

There are a lot of different opinions as to whether chewing gum is beneficial to your teeth or not. Are all chewing gums inevitably the same, or can some be better than others? Chewing gum can be good for you, but there are a few things we have to consider:

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Bad Breath

Causes, cures and its affects on your teeth

The medical term for bad breath is halitosis. Halitosis can result from poor dental hygiene habits and can also be a sign of other health problems. Types of food and other unhealthy lifestyle habits may also be causes of bad breath.

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Taking Care of your Baby’s teeth

It is recommended to start cleaning your baby’s mouth before their first tooth appears. You can start by taking a piece of gauze with water on it and wrap it around your finger then rub your baby’s gums and tongue. This should be done twice a day.

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Top 9 Foods that Damage Your Teeth

  1. Hard Candy – While hard candies can seem harmless, eat too many and the constant exposure to sugar can harm your teeth. Hard candies also put your teeth at risk for a broken or chipped tooth. A better alternative is chewing sugarless gum that carries the ADA Seal.
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How Much Can Braces Cost?

Braces are used to improve orofacial appearance. They straighten crooked/crowded teeth, fix overbites and under bites, and other orthodontic problems. Other problems may include speech difficulty and jaw disorders. These can be painful for the person by causing headaches, earaches, gum disease, and tooth decay.

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An Introduction of Root Canal

A Root Canal is a method in dentistry also known as “paying off the nerve”. In the Root Canal process the vascular nerve blocks inside the tooth causing enormous pain is extracted to avoid further suffering of a patient. With specialized equipment, teeth and gum area are cleaned achieving infection-free operation.

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Teeth Straightening Options

The invention of invisible braces has meant that more and more people are getting comfortable with wearing braces for straightening their teeth. However, there are many different ways to achieve a straight smile!

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